Reactivator

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Reactivator Report for: 6-Alkyl-3-Fluoro-2-pyridinaldoxime-12d

Name Class
6-Alkyl-3-Fluoro-2-pyridinaldoxime-12dType (3)
Chemical_NomenclatureN-[[3-fluoro-6-(2-pyridin-3-ylethyl)pyridin-2-yl]methylidene]hydroxylamine
FormulaC13H12FN3O
MW245.25
PaperYerri_2020_Chemistry_26_15035
Commentcompound 12d greater affinity and higher reactivation efficiency(kr2=83 mm-1.min-1) than 2-PAM and HI-6.Compound 12d seven times more efficient in the reactivation of sarin-inhibited AChE compared with 2-PAM,and six times more efficient than HI-6. Compound12d completely inefficient in reactivating tabun-inhibited hAChE
CID138559949
InChIKeyCKUUWPBCPYJLIA-UHFFFAOYSA-N
CanonicalSMILESC1=CC(=CN=C1)CCC2=NC(=C(C=C2)F)C=NO
InChIInChI=1S/C13H12FN3O/c14-12-6-5-11(17-13(12)9-16-18)4-3-10-2-1-7-15-8-10/h1-2,5-9,18H,3-4H2

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer