Structure Report for: 5FRD
| 5FRD | Name | Structure of a thermophilic esterase |
|---|
| Gene_locus | arcfu-est2 |
| Paper | Sayer_2016_Sci.Rep_6_25542 |
| PDB_file | 5frd-pdb |
| Substrate | Coenzyme-A |
| Family | 6_AlphaBeta_hydrolase |
| Comment | Sayer, C., Finnigan, W., Isupov, M.N., Levisson, M., Kengen, S.W.M., van der Oost, J., Harmer, N., Littlechild, J.A.:
A thermophilic esterase with high activity towards short- to medium-chain
p-nitrophenyl carboxylic esters with optimal activity towards the valerate ester.
The AF-Est2 has good solvent and pH stability and is very thermostable,
showing no loss of activity after incubation for 30min at 80 C.
The structure reveals a bound CoA molecule in the vicinity of the active site |
| Revelation_date | 25-May-2016 |
| News | MAY-25-2016 |
| | MAY-11-2016 |
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