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Substrate Report for: 4-MOMMP

Name Class
4-MOMMPTypePyridine
Chemical_NomenclatureN-(6-methoxy-2-methylpyridin-3-yl)-4-methyloctanamide
FormulaC16H26N2O2
MW278,3
PaperKodani_2017_Anal.Biochem_539_81
CommentTurnover 10 times lower than the model general esterase substrate CMNA. Its strong chemical stability allows to quantify low picogram levels of hCE1 when using an endpoint measurement over 24 hours. Its turnover by hCE1 is at least 10-fold more selective compared to 13 different serine hydrolases tested and 40- to 50-fold more selective compared to hCE2
Gene_locushuman-CES1
FamilyCarb_B_Chordata

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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