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Inhibitor Report for: [11C]N-methyl-tacrine

Name Class
[11C]N-methyl-tacrineTypeAcridine
Derivative of Tacrine
PET probe
Other_Name (7)
Chemical_Nomenclature[11C]N-methyl-tetrahydroamino-acridine
FormulaC14H16N2
MW211.29
PaperTavitian_1993_Eur.J.Pharmacol_236_229
Traykov_1999_Eur.J.Neurol_6_273
CommentReversible inhibitor of both AChE and BChE used in positron emission tomography (PET) imaging
CID192272
FamilyACHE
InChIKeyOBXGPCSAPSCKID-BJUDXGSMSA-N
CanonicalSMILESCNC1=C2CCCCC2=NC3=CC=CC=C31
InChIInChI=1S/C14H16N2/c1-15-14-10-6-2-4-8-12(10)16-13-9-5-3-7-11(13)14/h2,4,6,8H,3,5,7,9H2,1H3,(H,15,16)/i1-1

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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