Torpedo_number Report for: 288,290,330

human-ACHE : (kinetic parameters)

Mutation	Kin.	Type	Evaluation system	Effect	Reference
F295L/ F297V/ Y337A	kin	sdm	Acyl specificity	replacement of aromatic active center residues in human-ACHE by the corresponding residues in human-BCHE	Kaplan_2001_Biochemistry_40_7433, Barak_2005_Chem.Biol.Interact_157-158_219

mouse-ACHE

Mutation	Kin.	Type	Evaluation system	Effect	Reference
F295L/ F297I/ Y337A		sdm	oxime interaction	enlargement of the active site of the gorge	Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
F295L/ F297I/ Y337A		sdm	Oxime interaction		Kovarik_2004_Biochemistry_43_3222

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page