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Torpedo_number Report for: 226
danre-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S226N
Random
Silent variant
null mutation no activity
Behra_2002_Nat.Neurosci_5_111
human-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S229A
sdm
Catalysis
Conserved serine no activity
Shafferman_2005_Chem.Biol.Interact_157-158_123
ratno-Ces1d
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S247G
sdm
Conserved serine
5 fold loss of specific activity
Stok_2004_Arch.Biochem.Biophys_430_247
S247A
sdm
Conserved serine
15 fold loss of specific activity
Stok_2004_Arch.Biochem.Biophys_430_247
S247C
sdm
Conserved serine
not stable
Stok_2004_Arch.Biochem.Biophys_430_247
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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