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Torpedo_number Report for: 200
human-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S203A
sdm
Catalysis
No activity
Shafferman_1992_J.Biol.Chem_267_17640
S203A
sdm
Catalytic triad
No activity
Shafferman_1992_J.Biol.Chem_267_17640
S203C
sdm
Catalysis
1% activity cmp WT
Shafferman_1992_J.Biol.Chem_267_17640
S203C
sdm
Catalytic triad
1% activity cmp WT
Shafferman_1992_J.Biol.Chem_267_17640
S203T
sdm
Catalysis
No activity
Shafferman_1992_J.Biol.Chem_267_17640
S203T
sdm
Catalytic triad
No activity
Shafferman_1992_J.Biol.Chem_267_17640
human-BCHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S198G
nat
Natural mutation
Silent phenotype
Primo-Parmo_1992_4th.ChE.Meeting.Eilat__61
,
Primo-Parmo_1996_Am.J.Hum.Genet_58_52
S198C
sdm
Catalysis
1% activity compared to WT
Gnatt_1994_J.Neurochem_62_749
S198C
sdm
Catalytic triad
No activity
Gnatt_1994_J.Neurochem_62_749
S198Q
sdm
Catalysis
No activity
Gnatt_1994_J.Neurochem_62_749
S198Q
sdm
Catalytic triad
No activity
Gnatt_1994_J.Neurochem_62_749
S198H
sdm
Catalysis
No activity
Gnatt_1994_J.Neurochem_62_749
S198H
sdm
Catalytic triad
No activity
Gnatt_1994_J.Neurochem_62_749
S198D
sdm
Catalysis
No activity
Gnatt_1994_J.Neurochem_62_749
S198D
sdm
Catalytic triad
No activity
Gnatt_1994_J.Neurochem_62_749
mouse-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S203A
sdm
Catalytic triad
No activity
Bourne_2006_J.Biol.Chem_281_29256
torca-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
S200V
sdm
Catalysis
No activity
Gibney_1990_Proc.Natl.Acad.Sci.U.S.A_87_7546
S200V
sdm
Catalytic triad
No activity
Gibney_1990_Proc.Natl.Acad.Sci.U.S.A_87_7546
S200C
sdm
Catalysis
1% activity cmp WT
Gibney_1990_Proc.Natl.Acad.Sci.U.S.A_87_7546
S200C
sdm
Catalytic triad
1% activity cmp WT
Gibney_1990_Proc.Natl.Acad.Sci.U.S.A_87_7546
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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