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Torpedo_number Report for: 276
drome-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
V356A
sdm
Insecticide sensitivity
Boublik_2002_Protein.Eng_15_43
V356D
sdm
Binding of Triton X-100 studies
mutation mimic the torpedo enzyme, no effect
Marcel_2000_J.Biol.Chem_275_11603
human-BCHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
L274D
sdm
PROSS algorithm
Expression in E Coli
Brazzolotto_2017_Molecules_22_
mouse-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
D283N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
D280V/
D283N
sdm
Electrostatic
electrostatic influence reduced
Radic_1997_J.Biol.Chem_272_23265
E84Q/
E91Q/
D280V/
D283N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
E84Q/
E91Q/
D280V/
D283N/
D372N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
E84Q/
E91Q/
D280V/
D283N/
E292Q/
D372N
sdm
Electrostatic
electrostatic influence reduced, influences FAS2 inhibition and its ionic strength dependance
Radic_1997_J.Biol.Chem_272_23265
D74N/
D280V/
D283N
sdm
Electrostatic
mixed active center and surface charge mutant
Radic_1997_J.Biol.Chem_272_23265
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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