TSO

General

Type : Epoxide

Chemical_Nomenclature : (2S,3S)-2,3-diphenyloxirane

Canonical SMILES : C1=CC=C(C=C1)C2C(O2)C3=CC=CC=C3

InChI : InChI=1S\/C14H12O\/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12\/h1-10,13-14H\/t13-,14-\/m0\/s1

InChIKey : ARCJQKUWGAZPFX-KBPBESRZSA-N

Other name(s) : Trans-Stilbene oxide,     t-SO,     Trans-1,2-Diphenyloxirane,     (S,S)-stilbene oxide,     Trans-2,3-Diphenyloxirane,     UNII-D2L0AGD7AK,     Trans-alpha,alpha-Epoxydibenzyl


MW : 196.24

Formula : C14H12O

CAS_number :

PubChem :

UniChem :

Iuphar :

Target

Families : Epoxide_hydrolase

References (5)

Title : Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei - de Oliveira_2019_Mol.Biol.Rep_46_371
Author(s) : de Oliveira GS , Adriani PP , Wu H , Morisseau C , Hammock BD , Chambergo FS
Ref : Mol Biol Rep , 46 :371 , 2019
Abstract : de Oliveira_2019_Mol.Biol.Rep_46_371
ESTHER : de Oliveira_2019_Mol.Biol.Rep_46_371
PubMedSearch : de Oliveira_2019_Mol.Biol.Rep_46_371
PubMedID: 30426381
Gene_locus related to this paper: hypjq-g0r7e2

Title : Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics - Archelas_2016_Arch.Biochem.Biophys_591_66
Author(s) : Archelas A , Zhao W , Faure B , Iacazio G , Kotik M
Ref : Archives of Biochemistry & Biophysics , 591 :66 , 2016
Abstract : Archelas_2016_Arch.Biochem.Biophys_591_66
ESTHER : Archelas_2016_Arch.Biochem.Biophys_591_66
PubMedSearch : Archelas_2016_Arch.Biochem.Biophys_591_66
PubMedID: 26714303

Title : Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes - Amrein_2015_ACS.Catal_5_5702
Author(s) : Amrein BA , Bauer P , Duarte F , Carlsson AJ , Naworyta A , Mowbray SL , Widersten M , Kamerlin SCL
Ref : ACS Catal , 5 :5702 , 2015
Abstract : Amrein_2015_ACS.Catal_5_5702
ESTHER : Amrein_2015_ACS.Catal_5_5702
PubMedSearch : Amrein_2015_ACS.Catal_5_5702
PubMedID: 26527505
Gene_locus related to this paper: soltu-3epoxy

Title : Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis - Elfstrom_2006_Biochemistry_45_205
Author(s) : Elfstrom LT , Widersten M
Ref : Biochemistry , 45 :205 , 2006
Abstract : Elfstrom_2006_Biochemistry_45_205
ESTHER : Elfstrom_2006_Biochemistry_45_205
PubMedSearch : Elfstrom_2006_Biochemistry_45_205
PubMedID: 16388596
Gene_locus related to this paper: soltu-3epoxy

Title : The effect of tridiphane (2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane) on hepatic epoxide-metabolizing enzymes: indications of peroxisome proliferation - Moody_1987_Toxicol.Appl.Pharmacol_89_37
Author(s) : Moody DE , Hammock BD
Ref : Toxicol Appl Pharmacol , 89 :37 , 1987
Abstract : Moody_1987_Toxicol.Appl.Pharmacol_89_37
ESTHER : Moody_1987_Toxicol.Appl.Pharmacol_89_37
PubMedSearch : Moody_1987_Toxicol.Appl.Pharmacol_89_37
PubMedID: 3590187