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Substrate Report for: Pentanoylcholine

General
Type Trimethylammonium, Choline ester
Chemical_Nomenclature trimethyl(2-pentanoyloxyethyl)azanium
Canonical SMILES CCCCC(=O)OCC[N+](C)(C)C
InChI InChI=1S/C10H22NO2/c1-5-6-7-10(12)13-9-8-11(2,3)4/h5-9H2,1-4H3/q+1
InChIKey NDWNNGOMAATBHL-UHFFFAOYSA-N
Other name(s) Valerylcholine, Choline,valerate (ester) ; AC1L2BAT ; CTK4D2213 ; Trimethyl(2-pentanoyloxyethyl)azanium
________________________________________________________________________________________________
MW|188.28
Formula|C10H22NO2
CAS_number|16597-24-3, 2963-75-9 (iodide)
PubChem|18077
UniChem|NDWNNGOMAATBHL-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Pentanoylcholine ligand of proteins in family: BCHE
Protein | human-BCHE

References:
Search PubMed for references concerning: Pentanoylcholine
    Title: Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine.
    Lockridge O
    Ref: Pharmacol Ther, 47:35, 1990 : PubMed

            

    Title: The action of normal and atypical cholinesterase of human serum upon a series of esters of choline
    Davies RO, Marton AV, Kalow W
    Ref: Canadian Journal of Biochemistry & Pharmacology, 38:545, 1960 : PubMed

            


human-BCHE
MutationKmKcatConditionPaper
D70G 1500 uM 63000 /min   Lockridge_1990_Pharmacol.Ther_47_35
WT 720 uM 63000 /min   Lockridge_1990_Pharmacol.Ther_47_35

WT Kinetics
Kinetic parametersKmKcatConditionsPapers
human-BCHE720 uM63000 /min  Lockridge_1990_Pharmacol.Ther_47_35