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Substrate Report for: PHOME

fluorescent substrate of epoxide hydrolase


General
Type Fluorescent Probe, Epoxide, Cyanide, Naphthalen
Chemical_Nomenclature [cyano-(6-methoxynaphthalen-2-yl)methyl] 2-(3-phenyloxiran-2-yl)acetate
Canonical SMILES COC1=CC2=C(C=C1)C=C(C=C2)C(C#N)OC(=O)CC3C(O3)C4=CC=CC=C4
InChI InChI=1S/C23H19NO4/c1-26-19-10-9-16-11-18(8-7-17(16)12-19)21(14-24)27-22(25)13-20-23(28-20)15-5-3-2-4-6-15/h2-12,20-21,23H,13H2,1H3
InChIKey NZOVBSWOWQLAJG-UHFFFAOYSA-N
Other name(s) SCHEMBL1064361 ; HMS3650K18 ; AKOS032946385 ; SR-01000946299
________________________________________________________________________________________________
MW|373.40
Formula|C23H19NO4
CAS_number|1028430-42-3
PubChem|53394628
UniChem|NZOVBSWOWQLAJG-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | PHOME ligand of proteins in family: Epoxide_hydrolase

References:
Search PubMed for references concerning: PHOME
    Title: Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei
    de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS
    Ref: Mol Biol Rep, 46:371, 2019 : PubMed

            

    Title: Development of a high-throughput screen for soluble epoxide hydrolase inhibition
    Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD
    Ref: Analytical Biochemistry, 355:71, 2006 : PubMed