Naphthalene-1,2-epoxide

General

Type : Epoxide || Naphtyl ester || Naphthalen

Chemical_Nomenclature : 1a,7b-dihydronaphtho[1,2-b]oxirene

Canonical SMILES : C1=CC=C2C3C(O3)C=CC2=C1

InChI : InChI=1S\/C10H8O\/c1-2-4-8-7(3-1)5-6-9-10(8)11-9\/h1-6,9-10H

InChIKey : XQIJIALOJPIKGX-UHFFFAOYSA-N

Other name(s) : Naphthalene 1,2-oxide,     1a,7b-Dihydronaphth(1,2-b)oxirene,     1a,7b-dihydronaphtho[1,2-b]oxirene,     SCHEMBL50866,     CHEBI:52431


MW : 144.17

Formula : C10H8O

CAS_number : 17180-88-0

PubChem :

UniChem :

Iuphar :

Target

Families : Epoxide_hydrolase

References (3)

Title : Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene - Kitteringham_1996_J.Pharmacol.Exp.Ther_278_1018
Author(s) : Kitteringham NR , Davis C , Howard N , Pirmohamed M , Park BK
Ref : Journal of Pharmacology & Experimental Therapeutics , 278 :1018 , 1996
Abstract : Kitteringham_1996_J.Pharmacol.Exp.Ther_278_1018
ESTHER : Kitteringham_1996_J.Pharmacol.Exp.Ther_278_1018
PubMedSearch : Kitteringham_1996_J.Pharmacol.Exp.Ther_278_1018
PubMedID: 8819481

Title : Purification of human liver cytosolic epoxide hydrolase and comparison to the microsomal enzyme - Wang_1982_Biochemistry_21_5769
Author(s) : Wang P , Meijer J , Guengerich FP
Ref : Biochemistry , 21 :5769 , 1982
Abstract : Wang_1982_Biochemistry_21_5769
ESTHER : Wang_1982_Biochemistry_21_5769
PubMedSearch : Wang_1982_Biochemistry_21_5769
PubMedID: 6185139
Gene_locus related to this paper: human-EPHX1 , human-EPHX2

Title : Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes - Kapitulnik_1977_Clin.Pharmacol.Ther_21_158
Author(s) : Kapitulnik J , Levin W , Morecki R , Dansette PM , Jerina DM , Conney AH
Ref : Clinical Pharmacology & Therapeutics , 21 :158 , 1977
Abstract : Kapitulnik_1977_Clin.Pharmacol.Ther_21_158
ESTHER : Kapitulnik_1977_Clin.Pharmacol.Ther_21_158
PubMedSearch : Kapitulnik_1977_Clin.Pharmacol.Ther_21_158
PubMedID: 65238