NAPE
General
Type : Phospholipid || Phosphoethanolamine
Chemical_Nomenclature : [(2R)-3-[hydroxy-[2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]amino]ethoxy]phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate
Canonical SMILES : CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CCCC=CCC=CCC=CCC=CCCCCC)OC(=O)CCCCCCCC=CCCCCCCCC
InChI : InChI=1S\/C61H108NO9P\/c1-4-7-10-13-16-19-22-25-28-29-32-33-36-39-42-45-48-51-59(63)62-54-55-69-72(66,67)70-57-58(71-61(65)53-50-47-44-41-38-35-31-27-24-21-18-15-12-9-6-3)56-68-60(64)52-49-46-43-40-37-34-30-26-23-20-17-14-11-8-5-2\/h16,19,25-28,30-33,39,42,58H,4-15,17-18,20-24,29,34-38,40-41,43-57H2,1-3H3,(H,62,63)(H,66,67)\/b19-16-,28-25-,30-26-,31-27-,33-32-,42-39-\/t58-\/m1\/s1
InChIKey : WDNUSSOPDWPIPF-ANDZTLMQSA-N
Other name(s) : N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHEBI:85784, Q27158716, 1,2-dioleoyl-sn-glycero-3-phospho(N-arachidonoyl)ethanolamine, (2R,14Z,17Z,20Z,23Z)-5-hydroxy-2-{[(9Z)-octadec-9-enoyl]oxy}-5,10-dioxo-4,6-dioxa-9-aza-5lambda(5)-phosphanonacosa-14,17,20,23-tetraen-1-yl (9Z)-octadec-9-enoate
MW : 1030.5
Formula : C61H108NO9P
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : CGI-58_ABHD5_ABHD4
References (4)
| Title : ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice - Seramur_2023_J.Lipid.Res__100405 |
| Author(s) : Seramur ME , Sink S , O'Brien Cox A , Furdui CM , Key CC |
| Ref : J Lipid Res , :100405 , 2023 |
| Abstract : Seramur_2023_J.Lipid.Res__100405 |
| ESTHER : Seramur_2023_J.Lipid.Res__100405 |
| PubMedSearch : Seramur_2023_J.Lipid.Res__100405 |
| PubMedID: 37352974 |
| Gene_locus related to this paper: human-ABHD4 , mouse-abhd4 |
| Title : ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system - Lee_2015_Biochemistry_54_2539 |
| Author(s) : Lee HC , Simon GM , Cravatt BF |
| Ref : Biochemistry , 54 :2539 , 2015 |
| Abstract : Lee_2015_Biochemistry_54_2539 |
| ESTHER : Lee_2015_Biochemistry_54_2539 |
| PubMedSearch : Lee_2015_Biochemistry_54_2539 |
| PubMedID: 25853435 |
| Gene_locus related to this paper: human-ABHD4 |
| Title : Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases - Cognetta_2015_Chem.Biol_22_928 |
| Author(s) : Cognetta AB, 3rd , Niphakis MJ , Lee HC , Martini ML , Hulce JJ , Cravatt BF |
| Ref : Chemical Biology , 22 :928 , 2015 |
| Abstract : Cognetta_2015_Chem.Biol_22_928 |
| ESTHER : Cognetta_2015_Chem.Biol_22_928 |
| PubMedSearch : Cognetta_2015_Chem.Biol_22_928 |
| PubMedID: 26120000 |
| Title : Lipid profiling reveals tissue-specific differences for ethanolamide lipids in mice lacking fatty acid amide hydrolase - Kilaru_2010_Lipids_45_863 |
| Author(s) : Kilaru A , Isaac G , Tamura P , Baxter D , Duncan SR , Venables BJ , Welti R , Koulen P , Chapman KD |
| Ref : Lipids , 45 :863 , 2010 |
| Abstract : Kilaru_2010_Lipids_45_863 |
| ESTHER : Kilaru_2010_Lipids_45_863 |
| PubMedSearch : Kilaru_2010_Lipids_45_863 |
| PubMedID: 20714818 |