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Meprylcaine

General

Type : Local anesthetic || Not A\/B H target

Chemical_Nomenclature : [2-methyl-2-(propylamino)propyl] benzoate

Canonical SMILES : CCCNC(C)(C)COC(=O)C1=CC=CC=C1

InChI : InChI=1S\/C14H21NO2\/c1-4-10-15-14(2,3)11-17-13(16)12-8-6-5-7-9-12\/h5-9,15H,4,10-11H2,1-3H3

InChIKey : VXJABHHJLXLNMP-UHFFFAOYSA-N

Other name(s) : Oracaine, Epirocaine, Epirocain, SCHEMBL24631, CHEMBL127810, CHEBI:93147, ZINC2040457

MW : 235.32

Formula : C14H21NO2

CAS_number : 495-70-5

PubChem :

UniChem :

Iuphar :

Target

Families : BCHE

References (6)

Title : Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities - Morita_2005_Brain.Res_1057_153
Author(s) : Morita K , Hamamoto M , Arai S , Kitayama S , Irifune M , Kawahara M , Kihira K , Dohi T
Ref : Brain Research , 1057 :153 , 2005
Abstract : Morita_2005_Brain.Res_1057_153
ESTHER : Morita_2005_Brain.Res_1057_153
PubMedSearch : Morita_2005_Brain.Res_1057_153
PubMedID: 16125150

Title : Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics - Arai_2003_Brain.Res_964_83
Author(s) : Arai S , Morita K , Kitayama S , Kumagai K , Kumagai M , Kihira K , Dohi T
Ref : Brain Research , 964 :83 , 2003
Abstract : Arai_2003_Brain.Res_964_83
ESTHER : Arai_2003_Brain.Res_964_83
PubMedSearch : Arai_2003_Brain.Res_964_83
PubMedID: 12573515

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract : Lockridge_1990_Pharmacol.Ther_47_35
ESTHER : Lockridge_1990_Pharmacol.Ther_47_35
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : The intravenous toxicity of local anesthetic agents in man -
Author(s) : Foldes FF , Davidson GM , Duncalf D , Kuwabara S
Ref : Clinical Pharmacology & Therapeutics , 6 :328 , 1965
PubMedID: 14296030

Title : The use of radioiodinated serum albumin to confirm accidental intravascular insertion of epidural catheters -
Author(s) : Duncalf D , Foldes FF
Ref : Anesthesiology , 25 :564 , 1964
PubMedID: 14192803

Title : Studies on the pharmacology of meprylcaine (oracaine), a local anesthetic -
Author(s) : Truant AP
Ref : Archives Internationales de Pharmacodynamie et de Therapie , 115 :483 , 1958
PubMedID: 13572116