Idalopirdine-rivastigmine
General
Type : Drug || Pro-Drug || Indole || Carbamate || Derivative of Rivastigmine || Multitarget || 5-HT-receptor-ligand
Chemical_Nomenclature : [3-[[2-(6-fluoro-1H-indol-3-yl)ethylamino]methyl]phenyl] N-ethyl-N-methylcarbamate'
Canonical SMILES : C1(=C[N]C2=CC(=CC=C12)F)CCNCC3=CC(=CC=C3)OC(=O)N(C)CC
InChI : InChI=1S\/C21H24FN3O2\/c1-3-25(2)21(26)27-18-6-4-5-15(11-18)13-23-10-9-16-14-24-20-12-17(22)7-8-19(16)20\/h4-8,11-12,14,23-24H,3,9-10,13H2,1-2H3
InChIKey : QZGAFMLTVWNDEJ-UHFFFAOYSA-N
Other name(s) :
MW : 369.43
Formula : C21H24FN3O2
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : BCHE
References (1)
| Title : Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT(6) receptor antagonist with therapeutic interest in Alzheimer's disease - Toublet_2020_Eur.J.Med.Chem_210_113059 |
| Author(s) : Toublet FX , Lalut J , Hatat B , Lecoutey C , Davis A , Since M , Corvaisier S , Freret T , Sopkova-de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 210 :113059 , 2020 |
| Abstract : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| ESTHER : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| PubMedSearch : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| PubMedID: 33310288 |