Hepoxilin-A3

General

Type : Natural || Epoxide || Fatty acid

Chemical_Nomenclature : (5E,9E)-8-hydroxy-10-[3-[(E)-oct-2-enyl]oxiran-2-yl]deca-5,9-dienoic acid

Canonical SMILES : CCCCCC=CCC1C(O1)C=CC(CC=CCCCC(=O)O)O

InChI : InChI=1S\/C20H32O4\/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23\/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)\/b9-7+,10-6+,16-15+ || InChI=1S\/C20H32O4\/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23\/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)\/b9-7+,10-6+,16-15+\/t17?,18-,19-\/m0\/s1

InChIKey : SGTUOBURCVMACZ-LMIMMGIZSA-N || SGTUOBURCVMACZ-PDSTVSMRSA-N

Other name(s) : Hepoxilin A3,     Hepoxilin A,     Hepoxilin,     5,9-Decadienoic acid, 8-hydroxy-10-(3-(2-octenyl)oxiranyl)-,     AC1NS4FT,     trans-epoxy hydroxy eicosanoids hepoxilin A3,     8(R,S)-Hydroxy-11S,12S-epoxyeicosa-5Z,9E,14Z-trienoic acid,     (5E,9E)-8-hydroxy-10-[(2S,3S)-3-[(E)-oct-2-enyl]oxiran-2-yl]deca-5,9-dienoic acid


MW : 336.47

Formula : C20H32O4

CAS_number : 94161-11-2 || 85589-24-8

PubChem :

UniChem :

Iuphar :

Target

Families : Epoxide_hydrolase

References (3)

Title : Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase - Cronin_2011_J.Lipid.Res_52_712
Author(s) : Cronin A , Decker M , Arand M
Ref : J Lipid Res , 52 :712 , 2011
Abstract : Cronin_2011_J.Lipid.Res_52_712
ESTHER : Cronin_2011_J.Lipid.Res_52_712
PubMedSearch : Cronin_2011_J.Lipid.Res_52_712
PubMedID: 21217101

Title : Hepoxilin B3 and its enzymatically formed derivative trioxilin B3 are incorporated into phospholipids in psoriatic lesions - Anton_2002_J.Invest.Dermatol_118_139
Author(s) : Anton R , Camacho M , Puig L , Vila L
Ref : Journal of Investigative Dermatology , 118 :139 , 2002
Abstract : Anton_2002_J.Invest.Dermatol_118_139
ESTHER : Anton_2002_J.Invest.Dermatol_118_139
PubMedSearch : Anton_2002_J.Invest.Dermatol_118_139
PubMedID: 11851887

Title : Hepoxilin A3 is metabolized into its omega-hydroxy metabolite by human neutrophils -
Author(s) : Pace-Asciak CR , Reynaud D , Rounova O , Demin P , Pivnitsky KK
Ref : Advances in Experimental Medicine & Biology , 469 :535 , 1999
PubMedID: 10667379