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Substrate Report for: Glutaryl-7-aca

7,B-(4-Carboxybutanamido)cephalosporanic acid (glutaryl7-ACA) acylase is an enzyme which converts glutaryl7-ACAto7-aminocephalosporanic acid (7-ACA),a starting material for semisynthetic cephalosporin antibiotics


General
Type
Chemical_Nomenclature (6R,7R)-3-(acetyloxymethyl)-7-(4-carboxybutanoylamino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Canonical SMILES CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CCCC(=O)O)SC1)C(=O)O
InChI InChI=1S/C15H18N2O8S/c1-7(18)25-5-8-6-26-14-11(13(22)17(14)12(8)15(23)24)16-9(19)3-2-4-10(20)21/h11,14H,2-6H2,1H3,(H,16,19)(H,20,21)(H,23,24)/t11-,14-/m1/s1
InChIKey IXUSDMGLUJZNFO-BXUZGUMPSA-N
Other name(s) Glutaryl-7-aminocephalosporanic acid ; Gl-7-Aca ; glutaryl 7-aca ; SCHEMBL569055 ; CHEBI:41425 ; CTK1A5049 ; DTXSID40182197 ; glutaryl 7-aminocephalosporanic acid ; ZINC8927232 ; 7-Glutarylaminocephalosporanate
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MW|386.4
Formula|C15H18N2O8S
CAS_number|27920-90-7
PubChem|446570
UniChem|IXUSDMGLUJZNFO-BXUZGUMPSA-N
IUPHAR|
Wikipedia|

Target
Families | Glutaryl-7-aca ligand of proteins in family: Cocaine_esterase
Protein | brela-Q45289

References:
Search PubMed for references concerning: Glutaryl-7-aca
    Title: Cloning and nucleotide sequencing of a novel 7 beta-(4- carboxybutanamido)cephalosporanic acid acylase gene of Bacillus laterosporus and its expression in Escherichia coli and Bacillus subtilis.
    Aramori I, Fukagawa M, Tsumura M, Iwami M, Ono H, Kojo H, Kohsaka M, Ueda Y, Imanaka H
    Ref: Journal of Bacteriology, 173:7848, 1991 : PubMed