Dipivefrin

General

Type : Drug || Not A\/B H target || Pro-Drug || Propionate

Chemical_Nomenclature : [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate

Canonical SMILES : CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C

InChI : InChI=1S\/C19H29NO5\/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6\/h8-10,13,20-21H,11H2,1-7H3

InChIKey : OCUJLLGVOUDECM-UHFFFAOYSA-N

Other name(s) : Dipivefrine, Dipivefrinum, Dipivefrina, Dipivalyl epinephrine, AKPro


MW : 351.43

Formula : C19H29NO5

CAS_number :

PubChem :

UniChem :

Iuphar :

Target

Families : Carb_B_Chordata, ACHE, BCHE

References (4)

Title : Characterization of esterases involved in the hydrolysis of dipivefrin hydrochloride - Nakamura_1993_Ophthalmic.Res_25_46
Author(s) : Nakamura M , Shirasawa E , Hikida M
Ref : Ophthalmic Res , 25 :46 , 1993
Abstract : Nakamura_1993_Ophthalmic.Res_25_46
ESTHER : Nakamura_1993_Ophthalmic.Res_25_46
PubMedSearch : Nakamura_1993_Ophthalmic.Res_25_46
PubMedID: 8446367

Title : No changes in rabbit corneal esterase activities with dipivefrine hydrochloride instillation for 4 weeks -
Author(s) : Nakamura M , Shirasawa E , Hikida M
Ref : Graefes Arch Clin Exp Ophthalmol , 231 :551 , 1993
PubMedID: 8224961

Title : Effects of echothiophate on enzymatic hydrolysis of dipivefrin - Anderson_1984_Arch.Ophthalmol_102_913
Author(s) : Anderson JA , Richman JB , Mindel JS
Ref : Archives of Ophthalmologymol , 102 :913 , 1984
Abstract : Anderson_1984_Arch.Ophthalmol_102_913
ESTHER : Anderson_1984_Arch.Ophthalmol_102_913
PubMedSearch : Anderson_1984_Arch.Ophthalmol_102_913
PubMedID: 6732575

Title : The effect of echothiophate on the biphasic response of rabbit ocular pressure to dipivefrin - Mindel_1982_Arch.Ophthalmol_100_147
Author(s) : Mindel JS , Koenigsberg AM , Kharlamb AB , Goldfarb J , Orellana J
Ref : Archives of Ophthalmologymol , 100 :147 , 1982
Abstract : Mindel_1982_Arch.Ophthalmol_100_147
ESTHER : Mindel_1982_Arch.Ophthalmol_100_147
PubMedSearch : Mindel_1982_Arch.Ophthalmol_100_147
PubMedID: 6173032