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Cholesteryl-oleate

General

Type : Cholesterylester || Steroid || Oleate || Phenanthrene

Chemical_Nomenclature : [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate

Canonical SMILES : CCCCCCCCC=CCCCCCCCC(=O)OC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4C(C)CCCC(C)C)C)C

InChI : InChI=1S\/C45H78O2\/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44\/h14-15,26,35-36,38-42H,7-13,16-25,27-34H2,1-6H3\/b15-14-\/t36-,38+,39+,40-,41+,42+,44+,45-\/m1\/s1

InChIKey : RJECHNNFRHZQKU-RMUVNZEASA-N

Other name(s) : Oleoylcholesterol,     Cholesteryl cis-9-octadecenoate,     Oleic acid cholesteryl ester,     Cholest-5-en-3-beta-yl oleate,     Cholesteryl oleic ester,     Cholesteryl oleate,     cholesteryl (9Z-octadecenoate)

MW : 651.1

Formula : C45H78O2

CAS_number : 303-43-5

PubChem :

UniChem :

Iuphar :

Target

Families : Carboxylesterase, Acidic_Lipase, Carb_B_Chordata, Hormone-sensitive_lipase_like, Cholesterol_esterase, LIDHydrolase, Fungal_carboxylesterase_lipase, Arylacetamide_deacetylase

References (4)

Title : Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization - Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386
Author(s) : Goo YH , Son SH , Kreienberg PB , Paul A
Ref : Arterioscler Thromb Vasc Biol , 34 :386 , 2014
Abstract : Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386
ESTHER : Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386
PubMedSearch : Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386
PubMedID: 24357060
Gene_locus related to this paper: human-LDAH

Title : Mammalian carboxylesterases: from drug targets to protein therapeutics - Redinbo_2005_Drug.Discov.Today_10_313
Author(s) : Redinbo MR , Potter PM
Ref : Drug Discov Today , 10 :313 , 2005
Abstract : Redinbo_2005_Drug.Discov.Today_10_313
ESTHER : Redinbo_2005_Drug.Discov.Today_10_313
PubMedSearch : Redinbo_2005_Drug.Discov.Today_10_313
PubMedID: 15749280

Title : Structural insights into the lipase\/esterase behavior in the Candida rugosa lipases family: crystal structure of the lipase 2 isoenzyme at 1.97A resolution - Mancheno_2003_J.Mol.Biol_332_1059
Author(s) : Mancheno JM , Pernas MA , Martinez MJ , Ochoa B , Rua ML , Hermoso JA
Ref : Journal of Molecular Biology , 332 :1059 , 2003
Abstract : Mancheno_2003_J.Mol.Biol_332_1059
ESTHER : Mancheno_2003_J.Mol.Biol_332_1059
PubMedSearch : Mancheno_2003_J.Mol.Biol_332_1059
PubMedID: 14499609
Gene_locus related to this paper: canru-2lipa

Title : Purification, cloning, and expression of a human enzyme with acyl coenzyme A: cholesterol acyltransferase activity, which is identical to liver carboxylesterase - Becker_1994_Arterioscler.Thromb_14_1346
Author(s) : Becker A , Bottcher A , Lackner KJ , Fehringer P , Notka F , Aslanidis C , Schmitz G
Ref : Arterioscler Thromb , 14 :1346 , 1994
Abstract : Becker_1994_Arterioscler.Thromb_14_1346
ESTHER : Becker_1994_Arterioscler.Thromb_14_1346
PubMedSearch : Becker_1994_Arterioscler.Thromb_14_1346
PubMedID: 8049197
Gene_locus related to this paper: human-CES1 , pig-EST1