Type : Mycotoxin-metabolite || Macrolide || Natural || Toxin
Chemical_Nomenclature : (2E,7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,14,16-tetraen-13-one
Canonical SMILES : CC1CCCC(CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O)O
InChI : InChI=1S\/C18H24O5\/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12\/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3\/b7-3+\/t12-,14-\/m0\/s1
InChIKey : FPQFYIAXQDXNOR-PMRAARRBSA-N
Other name(s) : CHEMBL372840, CHEBI:35072, Beta zearalenol, beta-Zearalenol, beta-ZOL
Families : Zearalenone-hydrolase
Title : The Trp183 is essential in lactonohydrolase ZHD detoxifying zearalenone and zearalenols - Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
Author(s) : Zhou H , Li L , Zhan B , Wang S , Li J , Hu XJ |
Ref : Biochemical & Biophysical Research Communications , 522 :986 , 2020 |
Abstract : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
ESTHER : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
PubMedSearch : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
PubMedID: 31810602 |
Gene_locus related to this paper: biooc-ZHD101 |
Title : Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering - Xu_2016_ACS.Catal_6_7657 |
Author(s) : Xu Z , Liu W , Chen CC , Li Q , Huang JW , Ko TP , Liu G , Peng W , Cheng YS , Chen Y , Jin J , Li H , Zheng Y , Guo RT |
Ref : ACS Catal , 6 :7657 , 2016 |
Abstract : Xu_2016_ACS.Catal_6_7657 |
ESTHER : Xu_2016_ACS.Catal_6_7657 |
PubMedSearch : Xu_2016_ACS.Catal_6_7657 |
PubMedID: |
Gene_locus related to this paper: biooc-ZHD101 |