[I125]Methyl-4-piperidinyl-N-benzoate

General

Type : PET probe || Benzoate

Chemical_Nomenclature : (1-methylpiperidin-4-yl) 4-iodobenzoate

Canonical SMILES : CN1CCC(CC1)OC(=O)C2=CC=C(C=C2)I

InChI : InChI=1S\/C13H16INO2\/c1-15-8-6-12(7-9-15)17-13(16)10-2-4-11(14)5-3-10\/h2-5,12H,6-9H2,1H3

InChIKey : KRVXRNGJVZIXHS-UHFFFAOYSA-N

Other name(s) : 1-Methylpiperidin-4-yl 4-iodobenzoate,     [I125]MP4Bz,     CHEMBL83382,     SCHEMBL1839004,     BDBM50059308


MW : 345.18

Formula : C13H16INO2

CAS_number : 102698-62-4

PubChem :

UniChem :

Iuphar :

Target

Families : BCHE

References (3)

Title : Butyrylcholinesterase radioligands to image Alzheimer's disease brain - Darvesh_2013_Chem.Biol.Interact_203_354
Author(s) : Darvesh S
Ref : Chemico-Biological Interactions , 203 :354 , 2013
Abstract : Darvesh_2013_Chem.Biol.Interact_203_354
ESTHER : Darvesh_2013_Chem.Biol.Interact_203_354
PubMedSearch : Darvesh_2013_Chem.Biol.Interact_203_354
PubMedID: 22935510

Title : Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase - Macdonald_2011_Mol.Imaging.Biol_13_1250
Author(s) : Macdonald IR , Reid GA , Joy EE , Pottie IR , Matte G , Burrell S , Mawko G , Martin E , Darvesh S
Ref : Mol Imaging Biol , 13 :1250 , 2011
Abstract : Macdonald_2011_Mol.Imaging.Biol_13_1250
ESTHER : Macdonald_2011_Mol.Imaging.Biol_13_1250
PubMedSearch : Macdonald_2011_Mol.Imaging.Biol_13_1250
PubMedID: 20976626

Title : Synthesis of carbon-11- and fluorine-18-labeled 1-methyl-4-piperidyl-4'-fluorobenzoate and their biodistribution in mice - Bormans_1996_Nucl.Med.Biol_23_513
Author(s) : Bormans G , Sherman P , Snyder SE , Kilbourn MR
Ref : Nucl Med Biol , 23 :513 , 1996
Abstract : Bormans_1996_Nucl.Med.Biol_23_513
ESTHER : Bormans_1996_Nucl.Med.Biol_23_513
PubMedSearch : Bormans_1996_Nucl.Med.Biol_23_513
PubMedID: 8832709