DTS-108
General
Type : Drug || Not A\/B H target || Peptide
Chemical_Nomenclature :
Canonical SMILES :
InChI :
InChIKey :
Other name(s) : SN38-BCH-CVKRGLKLRHVRP
MW :
Formula :
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Carboxylesterase, Carb_B_Chordata
References (2)
| Title : Pharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study - Coriat_2016_Int.J.Nanomedicine_11_6207 |
| Author(s) : Coriat R , Faivre SJ , Mir O , Dreyer C , Ropert S , Bouattour M , Desjardins R , Goldwasser F , Raymond E |
| Ref : Int J Nanomedicine , 11 :6207 , 2016 |
| Abstract : Coriat_2016_Int.J.Nanomedicine_11_6207 |
| ESTHER : Coriat_2016_Int.J.Nanomedicine_11_6207 |
| PubMedSearch : Coriat_2016_Int.J.Nanomedicine_11_6207 |
| PubMedID: 27920527 |
| Title : DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies - Meyer-Losic_2008_Clin.Cancer.Res_14_2145 |
| Author(s) : Meyer-Losic F , Nicolazzi C , Quinonero J , Ribes F , Michel M , Dubois V , de Coupade C , Boukaissi M , Chene AS , Tranchant I , Arranz V , Zoubaa I , Fruchart JS , Ravel D , Kearsey J |
| Ref : Clin Cancer Research , 14 :2145 , 2008 |
| Abstract : Meyer-Losic_2008_Clin.Cancer.Res_14_2145 |
| ESTHER : Meyer-Losic_2008_Clin.Cancer.Res_14_2145 |
| PubMedSearch : Meyer-Losic_2008_Clin.Cancer.Res_14_2145 |
| PubMedID: 18381956 |