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Structure Report for: 8AEV

Name|Human acetylcholinesterase in complex with N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium
Revelation date|14-Jun-2023
Family|ACHE: there are 545 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Nachon, F.,Dias, J.,Brazzolotto, X.


    Title: Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions
    Nachon F, Brazzolotto X, Dias J, Courageux C, Drozdz W, Cao XY, Stefankiewicz AR, Lehn JM
    Ref: Chembiochem, 23:e202200456, 2022 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum8AEV Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP8AEV Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP8AEV Structural Classification Of Protein - SCOP server
PROTEOPEDIA8aev 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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