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Structure Report for: 7RB7

Name|Crystal structure of human acetylcholinesterase in complex with substrate analog 4K-TMA and MMB4 oxime
Revelation date|22-Sep-2021
Family|ACHE: there are 545 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Oksana Gerlits, Matthew P.Blakeley, David A.Keen, Zoran Radic, Andrey Kovalevsky
Ligand|Inhibitor: 4-oxo-N,N,N-trimethylpentanaminium Ligand in structure: Ligplot Reactivator: MMB-4 Ligand in structure: Ligplot


    Title: Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure
    Gerlits O, Blakeley MP, Keen DA, Radic Z, Kovalevsky A
    Ref: Current Research in Structural Biology, 3:206, 2021 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum7RB7 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7RB7 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7RB7 Structural Classification Of Protein - SCOP server
PROTEOPEDIA7rb7 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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