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Structure Report for: 7R0A

Name|Mus musculus Acetylcholinesterase inhibited by Sarin in complex with reactivator 4-methyl-3-nitrobenzamido-pentyl-PAM-7d
Revelation date|27-Apr-2022
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Ligand|Inhibitor: Sarin Ligand in structure: Ligplot Reactivator: 4-methyl-3-nitrobenzamido-pentyl-PAM-7d Ligand in structure: Ligplot


    Title: Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase
    Lindgren C, Forsgren N, Hoster N, Akfur C, Artursson E, Edvinsson L, Svensson R, Worek F, Ekstrom, Linusson A
    Ref: Chemistry, :, 2022 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum7R0A Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7R0A Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7R0A Structural Classification Of Protein - SCOP server
PROTEOPEDIA7r0a 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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