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Structure Report for: 7E3H

Name|Crystal structure of human acetylcholinesterase in complex with donepezil
Revelation date|16-Feb-2022
Family|ACHE: there are 544 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Dileep, K.V.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y.J.
Ligand|Inhibitor: Aricept~Donepezil~E2020 Ligand in structure: Ligplot


    Title: Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery
    Dileep KV, Ihara K, Mishima-Tsumagari C, Kukimoto-Niino M, Yonemochi M, Hanada K, Shirouzu M, Zhang KYJ
    Ref: Int J Biol Macromol, 210:172, 2022 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum7E3H Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7E3H Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7E3H Structural Classification Of Protein - SCOP server
PROTEOPEDIA7e3h 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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