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Structure Report for: 6Y0F

Name|Structure of human FAPalpha in complex with linagliptin
Revelation date|17-Feb-2021
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
Gene_locus|human-FAP
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Nar, H.,Schnapp, G.,Schreiner, P.
Ligand|Inhibitor: Linagliptin Ligand in structure: Ligplot


Reference

    Title: A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein
    Schnapp G, Hoevels Y, Bakker RA, Schreiner P, Klein T, Nar H
    Ref: ChemMedChem, 16:630, 2021 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum6Y0F Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6Y0F Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6Y0F Structural Classification Of Protein - SCOP server
PROTEOPEDIA6y0f 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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