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Structure Report for: 6XYY

Name|Update AChE from Drosophila Melanogaster complex with tacrine derivative 9-(3-phenylmethylamino)-1,2,3,4-tetrahydroacridine (1DX4)
Revelation date|18-Mar-2020
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Nachon, F., Sussman, J.L.
Ligand|Inhibitor: ZA Ligand in structure: Ligplot


    Title: A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides
    Nachon F, Rosenberry TL, Silman I, Sussman JL
    Ref: Molecules, 25:1198, 2020 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6XYY Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6XYY Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6XYY Structural Classification Of Protein - SCOP server
PROTEOPEDIA6xyy 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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