6M08
Name : Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor 6M08-BWO compound 7
Revelation date : 30-Dec-2020
Family : PAF-Acetylhydrolase
Gene_locus : human-PLA2G7
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Hu, H.C., Xu, Y.C.
Ligand :
References (1)
| Title : Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach - Huang_2020_J.Med.Chem_63_7052 |
| Author(s) : Huang F , Hu H , Wang K , Peng C , Xu W , Zhang Y , Gao J , Liu Y , Zhou H , Huang R , Li M , Shen J , Xu Y |
| Ref : Journal of Medicinal Chemistry , 63 :7052 , 2020 |
| Abstract : Huang_2020_J.Med.Chem_63_7052 |
| ESTHER : Huang_2020_J.Med.Chem_63_7052 |
| PubMedSearch : Huang_2020_J.Med.Chem_63_7052 |
| PubMedID: 32459096 |
| Gene_locus related to this paper: human-PLA2G7 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
