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Structure Report for: 6I5G

Name|X-ray structure of human soluble Epoxide yhdrolase C-terminal domain (hsEH CTD)in complex with 15d-PGJ2
Revelation date|29-May-2019
Family|Epoxide_hydrolase: there are 1166 genes in this family, 171 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Abis, G., Charles, R.L., Kopec, J., Yue, W.W., Atkinson, R.A., Bui, T.T.T., Lynham, S., Popova, S., Sun, Y.-B., Fraternali, F., Eaton, P., Conte, M.R.
Ligand|Inhibitor: 15d-PGJ2 Ligand in structure: Ligplot


Reference

    Title: 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
    Abis G, Charles RL, Kopec J, Yue WW, Atkinson RA, Bui TTT, Lynham S, Popova S, Sun YB and Conte MR <2 more author(s)>
    Ref: Commun Biol, 2:188, 2019 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum6I5G Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6I5G Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6I5G Structural Classification Of Protein - SCOP server
PROTEOPEDIA6i5g 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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