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Structure Report for: 6G1W

Name|Crystal structure of Torpedo Californica acetylcholinesterase in complex with 2-{1-[2-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]-1H-1,2,3-triazol-4-yl}-N-[4-(hydroxy)-3-methoxybenzyl]acetamide
Revelation date|04-Apr-2018
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Coquelle, N., Colletier, J.P. (This entry supersedes: 6FOV)
Ligand|Inhibitor: E0Z Ligand in structure: Ligplot


    Title: Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis
    Galdeano C, Coquelle N, Cieslikiewicz-Bouet M, Bartolini M, Perez B, Clos MV, Silman I, Jean L, Colletier JP and Munoz-Torrero D <1 more author(s)>
    Ref: Molecules, 23:, 2018 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6G1W Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6G1W Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6G1W Structural Classification Of Protein - SCOP server
PROTEOPEDIA6g1w 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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