6FR2
Name : Huamn soluble epoxide hydrolase in complex with LK864 polar spirocyclic orally bioavailable urea inhibitor
Revelation date : 12-Sep-2018
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Kramer, J.S., Pogoryelov, D., Krasavin, M., Proschak, E.
Ligand :
References (1)
| Title : Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase - Lukin_2018_Bioorg.Chem_80_655 |
| Author(s) : Lukin A , Kramer J , Hartmann M , Weizel L , Hernandez-Olmos V , Falahati K , Burghardt I , Kalinchenkova N , Bagnyukova D , Zhurilo N , Rautio J , Forsberg M , Ihalainen J , Auriola S , Leppanen J , Konstantinov I , Pogoryelov D , Proschak E , Dar'in D , Krasavin M |
| Ref : Bioorg Chem , 80 :655 , 2018 |
| Abstract : Lukin_2018_Bioorg.Chem_80_655 |
| ESTHER : Lukin_2018_Bioorg.Chem_80_655 |
| PubMedSearch : Lukin_2018_Bioorg.Chem_80_655 |
| PubMedID: 30059891 |
| Gene_locus related to this paper: human-EPHX2 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
