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Structure Report for: 6ARY

Name|Crystal structure of an insecticide-resistant acetylcholinesterase mutant (G119S) from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor
Revelation date|10-Jan-2018
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Cheung, J., Mahmood, A., Kalathur, R., Lixuan, L., Carlier, P.R.
Ligand|Inhibitor: Difluoromethyl-ketone-BT7 Ligand in structure: Ligplot


    Title: Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance
    Cheung J, Mahmood A, Kalathur R, Liu L, Carlier PR
    Ref: Structure, 26:130, 2018 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6ARY Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6ARY Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6ARY Structural Classification Of Protein - SCOP server
PROTEOPEDIA6ary 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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