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Structure Report for: 5UXZ

Name|X-ray crystal structure of Halotag (Haloalkane dehalogenase) bound to the P9 benzothiadiazole fluorogenic ligand
Revelation date|08-Mar-2017
Family|Haloalkane_dehalogenase-HLD2: there are 72 genes in this family, 130 structure(s)
Gene_locus|rhoso-halo1
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Depositors: Dunham, N.P., Boal, A.K. Mutations of rhoso-halo1: L47V, S58T, D78G, Y87F, L88M, C128F, A155T, E160K, A167V, A172T, K175M, C176G, K195N, A224E, N227D, E257K, T264A, H272N, Y273L
Ligand|Inhibitor: P9-benzothiadiazole Ligand in structure: Ligplot


Reference

    Title: The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification
    Liu Y, Miao K, Dunham NP, Liu H, Fares M, Boal AK, Li X, Zhang X
    Ref: Biochemistry, 56:1585, 2017 : PubMed

            



Representative scheme of Haloalkane_dehalogenase-HLD2 structure and an image from PDBsum server



Databases

PDB-Sum5UXZ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5UXZ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5UXZ Structural Classification Of Protein - SCOP server
PROTEOPEDIA5uxz 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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