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Structure Report for: 5TNS

Name|Crystal structure of the D129S mutant of the CFTR inhibitory factor Cif containing the adducted 7-oxa-bicyclo[4.1.0]heptane (epoxycyclohexane) (ECH) hydrolysis intermediate
Revelation date|11-Oct-2017
Family|CFTR-inhibitory-factor_Cif: there are 102 genes in this family, 42 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Hvorecny, K.L., Madden, D.R.
Ligand|Substrate: Cyclohexene-oxide Ligand in structure: Ligplot Inhibitor: 1,2-Cyclohexanediol Ligand in structure: Ligplot


    Title: Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase
    Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR
    Ref: Structure, 25:697, 2017 : PubMed


Representative scheme of CFTR-inhibitory-factor_Cif structure and an image from PDBsum server

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PDB-Sum5TNS Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5TNS Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5TNS Structural Classification Of Protein - SCOP server
PROTEOPEDIA5tns 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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