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Structure Report for: 5TNH

Name|Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 17,18-EpETE (epoxy-eicosatetraenoic acid) hydrolysis intermediate
Revelation date|11-Oct-2017
Family|CFTR-inhibitory-factor_Cif: there are 102 genes in this family, 45 structure(s)
Gene_locus|pseae-PA2934
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Hvorecny, K.L., Madden, D.R.
Ligand|Substrate: 17,18-EpETE Ligand in structure: Ligplot Inhibitor: 17,18-EpETE-product Ligand in structure: Ligplot


Reference

    Title: Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase
    Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR
    Ref: Structure, 25:697, 2017 : PubMed

            



Representative scheme of CFTR-inhibitory-factor_Cif structure and an image from PDBsum server

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Databases

PDB-Sum5TNH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5TNH Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5TNH Structural Classification Of Protein - SCOP server
PROTEOPEDIA5tnh 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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