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Structure Report for: 5LLS

Name|Porcine dipeptidyl peptidase IV in complex with 8-(3-aminopiperidin-1-yl)-7-[(2-bromophenyl)methyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Revelation date|14-Sep-2016
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Nar, H., Blaesse, M
Ligand|Inhibitor: 6Z8 Ligand in structure: Ligplot


    Title: Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase-4 Inhibitors and Their Relationship to Structure
    Schnapp G, Klein T, Hoevels Y, Bakker RA, Nar H
    Ref: Journal of Medicinal Chemistry, 59:7466, 2016 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum5LLS Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5LLS Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5LLS Structural Classification Of Protein - SCOP server
PROTEOPEDIA5lls 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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