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Structure Report for: 5JAR

Name|Exploitation of a novel binding pocket in human Lipoprotein-associated Phospholipase A2 (Lp-PLA2) discovered through X-Ray fragment screening
Revelation date|25-May-2016
Family|PAF-Acetylhydrolase: there are 145 genes in this family, 35 structure(s)
Gene_locus|human-PLA2G7
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Day, P.J.
Ligand|


Reference

    Title: Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening
    Woolford AJ, Pero JE, Aravapalli S, Berdini V, Coyle JE, Day PJ, Dodson AM, Grondin P, Holding FP and Xie R <19 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:5356, 2016 : PubMed

            



Representative scheme of PAF-Acetylhydrolase structure and an image from PDBsum server



Databases

PDB-Sum5JAR Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5JAR Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5JAR Structural Classification Of Protein - SCOP server
PROTEOPEDIA5jar 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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