5ISM

Name : Human DPP4 in complex with a novel 5,5,6-tricyclic pyrrolidine inhibitor

Revelation date : 11-May-2016

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Scapin, G

Ligand :

References (1)

Title : The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors - Cox_2016_Bioorg.Med.Chem.Lett_26_2622

Author(s) : Cox JM , Chu HD , Kuethe JT , Gao YD , Scapin G , Eiermann G , He H , Li X , Lyons KA , Metzger J , Petrov A , Wu JK , Xu S , Sinha-Roy R , Weber AE , Biftu T

Ref : Bioorganic & Medicinal Chemistry Lett , 26 :2622 , 2016

Abstract : Cox_2016_Bioorg.Med.Chem.Lett_26_2622

ESTHER : Cox_2016_Bioorg.Med.Chem.Lett_26_2622

PubMedSearch : Cox_2016_Bioorg.Med.Chem.Lett_26_2622

PubMedID: 27106708

Gene_locus related to this paper: human-DPP4

5ISM

References (1)

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

5ISM

References (1)

1. The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases