Tree Display

AceDB Schema

XML Display


Structure Report for: 5HF9

Name|Crystal structure of human acetylcholinesterase in complex with paraoxon and HI-6
Revelation date|22-Jun-2016
Family|ACHE: there are 544 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Franklin, M.F., Rudolph, M.J., Ginter, C., Cassidy, M.S., Cheung, J
Ligand|Inhibitor: Paraoxon Ligand in structure: Ligplot Inhibitor: Diethyl-hydrogen-phosphate Ligand in structure: Ligplot Reactivator: HI-6 Ligand in structure: Ligplot


    Title: Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface
    Franklin MC, Rudolph MJ, Ginter C, Cassidy MS, Cheung J
    Ref: Proteins, 84:1246, 2016 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum5HF9 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5HF9 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5HF9 Structural Classification Of Protein - SCOP server
PROTEOPEDIA5hf9 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer