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Structure Report for: 5FPP

Name|Structure of a pre-reaction ternay complex between sarin- acetylcholinesterase and HI-6
Revelation date|11-May-2016
Family|ACHE: there are 545 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Allgardsson, A., Berg, L., Akfur, C., Hornberg, A., Worek, F., Linusson, A., Ekstrom, F.
Ligand|Inhibitor: Sarin Ligand in structure: Ligplot Reactivator: HI-6 Ligand in structure: Ligplot


    Title: Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
    Allgardsson A, Berg L, Akfur C, Hornberg A, Worek F, Linusson A, Ekstrom F
    Ref: Proc Natl Acad Sci U S A, 113:5514, 2016 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum5FPP Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5FPP Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5FPP Structural Classification Of Protein - SCOP server
PROTEOPEDIA5fpp 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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