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Structure Report for: 5DTJ

Name|Crystal Structure of DFP-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134
Revelation date|21-Oct-2015
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Tong, L., Tran, T.H.
Ligand|Inhibitor: DFP Ligand in structure: Ligplot Reactivator: SP-134 Ligand in structure: Ligplot


    Title: Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates
    Katz FS, Pecic S, Tran TH, Trakht I, Schneider L, Zhu Z, Ton-That L, Luzac M, Zlatanic V and Stojanovic MN <4 more author(s)>
    Ref: Chembiochem, 16:2205, 2015 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum5DTJ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5DTJ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5DTJ Structural Classification Of Protein - SCOP server
PROTEOPEDIA5dtj 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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