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Structure Report for: 4UZ6

Name|Structure of the wnt deacetylase notum - Crystal form V SOS complex - 1.9A
Revelation date|25-Feb-2015
Family|Pectinacetylesterase-Notum: there are 695 genes in this family, 143 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Kakugawa, S., Langton, P.F., Zebisch, M., Howell, S.A., Chang, T.-H., Liu, Y., Feizi, T., Bineva, G., O'Reilly, N., Snijders, A.P., Jones, E.Y., Vincent, J.-P.
Ligand|Inhibitor: Sucrose-octasulfate Ligand in structure: Ligplot


    Title: Notum deacylates Wnt proteins to suppress signalling activity
    Kakugawa S, Langton PF, Zebisch M, Howell SA, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N and Vincent JP <2 more author(s)>
    Ref: Nature, 519:187, 2015 : PubMed


Representative scheme of Pectinacetylesterase-Notum structure and an image from PDBsum server

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PDB-Sum4UZ6 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4UZ6 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4UZ6 Structural Classification Of Protein - SCOP server
PROTEOPEDIA4uz6 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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