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Structure Report for: 4EY7

Name|Crystal Structure of recombinant human acetylcholinesterase in complex with Donepezil
Revelation date|17-Oct-2012
Family|ACHE: there are 546 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Cheung, J., Rudolph, M., Burshteyn, F., Cassidy, M., Gary, E., Love, J., Height, J., Franklin, M.
Ligand|Inhibitor: Aricept~Donepezil~E2020 Ligand in structure: Ligplot


    Title: Structures of human acetylcholinesterase in complex with pharmacologically important ligands
    Cheung J, Rudolph MJ, Burshteyn F, Cassidy MS, Gary EN, Love J, Franklin MC, Height JJ
    Ref: Journal of Medicinal Chemistry, 55:10282, 2012 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum4EY7 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4EY7 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4EY7 Structural Classification Of Protein - SCOP server
PROTEOPEDIA4ey7 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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