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Structure Report for: 3O95

Name|Crystal Structure of Human DPP4 Bound to TAK-100
Revelation date|26-Jan-2011
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Yano, J.K., Aertgeerts,K.
Ligand|Inhibitor: TAK-100 Ligand in structure: Ligplot


    Title: Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor
    Miyamoto Y, Banno Y, Yamashita T, Fujimoto T, Oi S, Moritoh Y, Asakawa T, Kataoka O, Yashiro H and Maezaki H <12 more author(s)>
    Ref: Journal of Medicinal Chemistry, 54:831, 2011 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum3O95 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3O95 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3O95 Structural Classification Of Protein - SCOP server
PROTEOPEDIA3o95 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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