3O95
Name : Crystal Structure of Human DPP4 Bound to TAK-100
Revelation date : 26-Jan-2011
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Yano, J.K., Aertgeerts,K.
Ligand :
References (1)
| Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Journal of Medicinal Chemistry , 54 :831 , 2011 |
| Abstract : Miyamoto_2011_J.Med.Chem_54_831 |
| ESTHER : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedID: 21218817 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
