Structure

Tree Display

AceDB Schema

XML Display

Feedback

Structure Report for: 3KWJ

Name|Strucutre of human DPP-IV with (2S,3S,11bS)-3-(3-Fluoromethyl-phenyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine
Revelation date|15-Sep-2010
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
Gene_locus|human-DPP4
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Hennig, M., Stihle, M., Thoma, R.
Ligand|Inhibitor: 23Q Ligand in structure: Ligplot


Reference

    Title: Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors
    Boehringer M, Fischer H, Hennig M, Hunziker D, Huwyler J, Kuhn B, Loeffler BM, Luebbers T, Mattei P and Wessel HP <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:1106, 2010 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

no Image


Databases

PDB-Sum3KWJ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3KWJ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3KWJ Structural Classification Of Protein - SCOP server
PROTEOPEDIA3kwj 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer