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Structure Report for: 3K9B

Name|Crystal Structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Revelation date|19-Jan-2010
Family|Carb_B_Chordata: there are 543 genes in this family, 22 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Hemmert, A.C., Otto, T.C., Weirdl, M., Potter, P.M., Cerasoli, D.M., Redinbo, M.R.
Ligand|Inhibitor: Cyclosarin Ligand in structure: Ligplot


    Title: Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
    Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR
    Ref: Molecular Pharmacology, 77:508, 2010 : PubMed


Representative scheme of Carb_B_Chordata structure and an image from PDBsum server


PDB-Sum3K9B Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3K9B Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3K9B Structural Classification Of Protein - SCOP server
PROTEOPEDIA3k9b 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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