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Structure Report for: 2Y1K

Name|Structure of Human Butyrylcholinesterase Inhibited by CBDP (12h soak) : Phosphoserine Adduct
Revelation date|29-Jun-2011
Family|BCHE: there are 91 genes in this family, 92 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Carletti, E., Colletier, J.P., Nachon, F., Weik, M.
Ligand|Inhibitor: CBDP Ligand in structure: Ligplot


    Title: Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis
    Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P
    Ref: Chemical Research in Toxicology, 24:797, 2011 : PubMed


Representative scheme of BCHE structure and an image from PDBsum server


PDB-Sum2Y1K Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2Y1K Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2Y1K Structural Classification Of Protein - SCOP server
PROTEOPEDIA2y1k 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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