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Structure Report for: 2X8B

Name|Crystal structure of human acetylcholinesterase inhibited by aged tabun and complexed with fasciculin-II
Revelation date|28-Apr-2010
Family|ACHE: there are 541 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Carletti, E., Colletier, J.P., Nachon, F.
Ligand|Inhibitor: Tabun Ligand in structure: Ligplot Inhibitor: Fasciculin2 Ligand in structure: Ligplot


    Title: Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation
    Carletti E, Colletier JP, Dupeux F, Trovaslet M, Masson P, Nachon F
    Ref: Journal of Medicinal Chemistry, 53:4002, 2010 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum2X8B Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2X8B Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2X8B Structural Classification Of Protein - SCOP server
PROTEOPEDIA2x8b 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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