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Structure Report for: 2QTB

Name|Human dipeptidyl peptidase IV/CD26 in complex with 4-aryl cyclohexylanine inhibitor 1
Revelation date|06-Nov-2007
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Kaelin, D.E., Smetin, A.L, Eiermann, G.J., He, H., Leiting, B., Lyons, K.A., Patel, R.A, Patel, S.B, Petrov, A., Scapin, G., Wu, J.K., Thornberry, N.A, Weber, A.E, Duffy, J.L.
Ligand|Inhibitor: 4-aryl-cyclohexylalanine-inhibitor-1 Ligand in structure: Ligplot


    Title: 4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV
    Kaelin DE, Smenton AL, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A and Duffy JL <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:5806, 2007 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2QTB Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2QTB Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2QTB Structural Classification Of Protein - SCOP server
PROTEOPEDIA2qtb 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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